California. Institute to Advance Personalized Medicine Funds UCSF-CGEH investigator Elad Ziv

California Institute to Advance Precision Medicine: Improving Precision Medicine for Breast Cancer in Latinas: A multi-tiered Approach

This project will aim to improve both hereditary (germline) genetic prediction of breast cancer risk and to understand the landscape of cancer-specific (somatic) genetic mutations in breast cancer from Latina women. We will use data from germline genetic analysis of over 14,000 Latinas including 5000 specifically recruited for this study, and tumor/normal mutational analysis from ~500 women to understand the landscape of breast cancer genomics in Latinas. This project will help improve risk prediction for breast cancer in Latinas and will help to improve targeted treatment of breast cancer in Latina women.

During his talk entitled, “Addressing Disparities in Breast Cancer in Latinas: A Multi-Tiered Approach,” Dr. Ziv discussed how his team determined which genetic variants are associated with breast cancer in Latinas and increased community awareness of hereditary cancer and genetic testing.

Learn more: CIAPM - Addressing Disparities in Breast Cancer in Latinas: A Multi-Tiered Approach